Single-cell analysis of Crohn's disease reveals a detailed picture of inflammation in the gut

Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn
Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes inflammation throughout the gut, leading to symptoms including abdominal pain, diarrhea, and weight loss. The disease is difficult to treat and often requires hospitalization.

Immune responses in chronic inflammatory bowel diseases - New population of immune cells that is highly abundant in Crohn's disease patients

Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn's disease: a multi-omics Mendelian randomization study, BMC Medicine

Peter V. on LinkedIn: Single-cell analysis of Crohn's disease

Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn's disease patients

Cytoskeletal Organization and Cell Polarity in the Pathogenesis of Crohn's Disease

Inflammatory bowel disease

Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn's Disease - ScienceDirect

Single-cell atlas reveals underlying building blocks of ulcerative colitis – MIT Department of Chemistry

Single-cell analysis of Crohn's disease reveals a detailed picture of

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