Skin tissue regeneration for burn injury

The skin is the largest organ of the body, which meets the environment most directly. Thus, the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a serious interaction between cell types, cytokines, mediators, the neurovascular system, and matrix remodeling. Tissue regeneration technology remarkably enhances skin repair via re-epidermalization, epidermal-stromal cell interactions, angiogenesis, and inhabitation of hypertrophic scars and keloids. The success rates of skin healing for burn injuries have significantly increased with the use of various skin substitutes. In this review, we discuss skin replacement with cells, growth factors, scaffolds, or cell-seeded scaffolds for skin tissue reconstruction and also compare the high efficacy and cost-effectiveness of each therapy. We describe the essentials, achievements, and challenges of cell-based therapy in reducing scar formation and improving burn injury treatment.

Skin tissue engineering advances in severe burns: review and

Accelerated burn wound healing with photobiomodulation therapy invol

Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization, Stem Cell Research & Therapy

Skin Regeneration After Burns Skin Healing After Burns 2024

bFGF and collagen matrix hydrogel attenuates burn wound

Burn injury Nature Reviews Disease Primers

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Burn wounds. (A) First degree. (B) Superficial second degree. (C)

wound healing – NIH Director's Blog

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Heparin mimetic peptide nanofiber gel promotes regeneration of full thickness burn injury.

In situ scarless skin healing of a severe human burn wound induced

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Treatment of murine partial thickness scald injuries with multipotent adult progenitor cells decreases inflammation and promotes angiogenesis leading to improved burn injury repair - Ahangar - 2021 - Wound Repair and Regeneration - Wiley Online Library

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