By A Mystery Man Writer
Download scientific diagram | Iron recycling and distribution in the body. Body iron is primarily located in erythrocytes (>70%) which are efficiently recycled by macrophages of the liver and spleen. Enterocytes obtain iron from the diet. Macrophages, which obtain iron from the phagocytosis of senescent RBCs release iron into the circulation where it binds to plasma transferrin, the iron transport protein. Transferrin delivers iron to the erythron of the bone marrow and to other sites like hepatocytes of the liver, the main iron storage site in the body. There is no physiological excretion pathway for iron. from publication: Polymeric nanocarriers for the treatment of systemic iron overload | Desferrioxamine (DFO), deferiprone (L1) and desferasirox (ICL-670) are clinically approved iron chelators used to treat secondary iron overload. Although iron chelators have been utilized since the 1960s and there has been much improvement in available therapy, there is still | Iron Overload, Chelating Agents and Iron | ResearchGate, the professional network for scientists.
Targeting iron metabolism in drug discovery and delivery
Iron overload in alcoholic liver disease: underlying mechanisms
A simple scheme of iron absorption, distribution and recycling in
2: Iron absorption and recycle in human body
Hepcidin hi-res stock photography and images - Alamy
How the kidney contributes to healthy iron levels and disease
Iron Metabolism
Reusable Metal Straws — Design Life-Cycle
Distribution of body iron. The adult human body has approximately
IJMS, Free Full-Text
Iron recycling and distribution in the body. Body iron is
PDF) Polymeric nanocarriers for the treatment of systemic iron
Pumping iron”—how macrophages handle iron at the systemic
Molecules, Free Full-Text
Frontiers Iron and Chronic Kidney Disease: Still a Challenge